Strategy and Statistics in Clinical Trials
A non-statisticians guide to thinking, designing and executing
(Sprache: Englisch)
Strategy and Statistics in Clinical Trials is for all individuals engaged in clinical research, including professors, physicians, researchers in corporate and government laboratories, nurses, members of the allied health professions, and post-doctoral and...
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Produktdetails
Produktinformationen zu „Strategy and Statistics in Clinical Trials “
Strategy and Statistics in Clinical Trials is for all individuals engaged in clinical research, including professors, physicians, researchers in corporate and government laboratories, nurses, members of the allied health professions, and post-doctoral and graduate students who are potentially less exposed to understanding the pivotal role of statistics.
Enables nonstatisticians to better understand research processes and statistics' role in these processes Offers real-life case studies and provides a practical, "how to" guide to biomedical R&D Delineates the statistical building blocks and concepts of clinical trials Promotes effective cooperation between statisticians and important other parties
Enables nonstatisticians to better understand research processes and statistics' role in these processes Offers real-life case studies and provides a practical, "how to" guide to biomedical R&D Delineates the statistical building blocks and concepts of clinical trials Promotes effective cooperation between statisticians and important other parties
Klappentext zu „Strategy and Statistics in Clinical Trials “
Strategy and Statistics in Clinical Trials deals with the research processes and the role of statistics in these processes. The book offers real-life case studies and provides a practical, how to guide to biomedical R&D. It describes the statistical building blocks and concepts of clinical trials and promotes effective cooperation between statisticians and important other parties.
The discussion is organized around 15 chapters. After providing an overview of clinical development and statistics, the book explores questions when planning clinical trials, along with the attributes of medical products. It then explains how to set research objectives and goes on to consider statistical thinking, estimation, testing procedures, and statistical significance, explanation and prediction. The rest of the book focuses on exploratory and confirmatory clinical trials; hypothesis testing and multiplicity; elements of clinical trial design; choosing trial endpoints; and determination of sample size.
This book is for all individuals engaged in clinical research who are interested in a better understanding of statistics, including professional clinical researchers, professors, physicians, and researchers in laboratory. It will also be of interest to corporate and government laboratories, clinical research nurses, members of the allied health professions, and post-doctoral and graduate students.
Inhaltsverzeichnis zu „Strategy and Statistics in Clinical Trials “
Chapter 1.) Clinical Development and Statistics: The General ViewChapter 2.) Questions when Planning TrialsChapter 3.) Medical Product AttributesChapter 4.) Setting Research ObjectivesChapter 5.) Statistical ThinkingChapter 6.) EstimationChapter 7.) From Description to Testing: A BeginningChapter 8.) Statistical Significance, Explanation and PredictionChapter 9.) Exploratory and Confirmatory Clinical TrialsChapter 10.) One, Two, Three Testing: Hypothesis Testing and MultiplicityChapter 11.) Elements of Clinical Trial Design I: Putting it togetherChapter 12.) Elements of Clinical Trial Design IIChapter 13.) Choosing Trial EndpointsChapter 14.) Determination of Sample SizeChapter 15.) Concluding Remarks
Bibliographische Angaben
- Autor: Joseph Tal
- 2011, 267 Seiten, Maße: 19,1 x 23,6 cm, Gebunden, Englisch
- Verlag: Academic Press
- ISBN-10: 0123869099
- ISBN-13: 9780123869098
Sprache:
Englisch
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