Structure, Function and Regulation of TOR complexes from Yeasts to Mammals

Chapter 1: TOR complexes: composition, structure and phosphorylationMike HallChapter 2: Regulation of TOR signaling in mammalsDudley W. Lamming and David SabatiniChapter 3: Rheb G-protein and activation of mTORC1Fuyu TamanoiChapter 4: Regulation of TOR Complex1 by amino acids through small GTPasesJoe Avruch, Xiaomeng Long, Yenshou Lin, Sara Ortiz-Vega, Joseph Rapley, and Noriko OshiroChapter 5: Rag GTPases in TORC1 activation and nutrient signalingLi Li and Kun-Liang Guan Chapter 6: Amino Acid Regulation of hVps34 and mTORC1 signalingPawan Gulati and George ThomasChapter 7: mTORC1 and cell cycle controlChris ProudChapter 8: AGC Kinases in mTOR SignalingEstela Jacinto Chapter 9: TORC1 signaling in budding yeastRobbie Loewith Chapter 10: TORC2 and sphingolipid biosynthesis and signaling: Lessons from budding yeast

Ted PowersChapter 11: TORC1 signaling in the budding yeast endomembrane system and control of cell-cell adhesion in pathogenic fungiRobert J. Bastidas and Maria Cardenas-CoronaChapter 12: TOR and sexual development in fission yeastYoko Otsubo and Masayuki YamamotoChapter 13: Fission yeast TOR and rapamycinRonit Weisman Chapter 14: Structure of TOR complexes in fission yeastJunko Kanoh and Mitsuhiro YanagidaChapter 15: The TOR complex and signaling pathway in plantsChristophe Robaglia, Bruce Veit and Christian MeyerChapter 16: Dysregulation of TOR Signaling in Tuberous Sclerosis and Lymphangioleiomyomotosis Elizabeth Henske Chapter 17: Chemistry and Pharmacology of Rapamycin and its DerivativesRobert T. Abraham, James J. Gibbons and Edmund I. Graziani

Fuyu Tamanoi is a biochemist who has served on the UCLA School of Medicine and UCLA College faculty since he joined the Department of Microbiology, Immunology & Molecular Genetics in 1993. He became a full professor in 1997.