Structure-Function Relationships of Human Pathogenic Viruses

1. Cell entry and egress. 1.1. Epstein-Barr Virus Glycoproteins and their Roles in Virus Entry and Egress; L. Hutt-Fletcher. 1.2. Structure and Function of Viral Glycoproteins in Membrane Fusion; W. Weissenhorn. 2. Viral replication. 2.1. Viral RNA-directed Polymerases: Structure and Function Relationships; J. Jäger, J.D. Pata. 2.2. Marburg Virus Replication and Nucleocapsid Formation: Different Jobs, Same Players; E. Mühlberger, S. Becker. 3. Viral determinants for capsid formation and packaging. 3.1. Packaging DNA into Herpesvirus Capsids; J.C. Brown, et al. 3.2. From Concatemeric DNA into Unit-length Genomes - a Miracle or Clever Genes? A. Holzenburg, E. Bogner. 4. Determinants for viral maturation. 4.1. Role of Envelope Proteins in Measles Virus Assembly; A. Maisner. 4.2. The Predominant Varicella-zoster Virus gE and gI Glycoprotein Complex; C. Grose. 4.3. Expression Strategy and Functions of the Filoviral Glycoproteins; V.E. Volchkov, H. Feldman. 5. Pathogenesis. 5.1. Prions: When Proteins Take a Wrong Turn; A. Bellon, M. Vey. 5.2. Human Immunodeficiency Virus: From Virus Structure to Pathogenesis; H. Gelderblom, K. Boller. 5.3. The role of Hemagglutinin and Neuraminidase in Influenza Virus Pathogenesis; R. Wagner, et al. 6. Viral oncogenesis. 6.1. Rhadinovirus Pathogenesis; A. Ensser, et al. 6.2. Interaction of Papillomaviral Oncoproteins with Cellular Factors; S. Smola-Hess, H.J. Pfister. 7. Defense mechanisms. 7.1. Cytomegaloviral Glycoprotein Interacting with MHC Class I Moleculesand the MHC-encoded Peptide Transporter; A. Zimmermann, et al. 7.2. Regulation of Cellular Genes by Cytomegalovirus; M.F. Stinski, Yoon-Jae Song. Index.