Technical Aspects of Toxicological Immunohistochemistry
System Specific Biomarkers
(Sprache: Englisch)
This authoritative volume examines immunohistochemical methods aimed at investigating the toxicologic pathology of rodent, non-human primate and aquatic animal tissues. Eleven comprehensive chapters provide pathologists and researchers in various...
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Klappentext zu „Technical Aspects of Toxicological Immunohistochemistry “
This authoritative volume examines immunohistochemical methods aimed at investigating the toxicologic pathology of rodent, non-human primate and aquatic animal tissues. Eleven comprehensive chapters provide pathologists and researchers in various sub-disciplines of toxicology with a comprehensive review of the methods and approaches for immunohistochemical staining in various target tissues. It explores the tissue-antigen and antibody-specific problems that may be encountered during the staining procedures and provide potential avenues for resolving various methodological issues. Special attention is paid to the latest enhancement procedures for antigen retrieval and visualization as well as image analysis and antigen quantification. Written by leading researchers in toxicology and pathology, this book is a significant resource for toxicologists and pathologists working with rodents, monkeys and aquatic animal tissues.
Inhaltsverzeichnis zu „Technical Aspects of Toxicological Immunohistochemistry “
1 Antigen Retrieval2 Tissue Microarray and its importance in Toxicology
3 Significance of Double immunostain in Toxicology
4 The role of apoptosis and its marker in toxicological evaluation
5 Toxicological effect of apoptosis and proliferation
6 Biomarkers of skeletal muscle injury in the rat
7 Breast tumour markers; a toxicological evaluation in rodents
8 Rodent colon markers
9 Immunohistochemistry of intestinal track
10 Evaluation of Lung Immunohistochemistry in rodent
11 Immunohistochemistry of circulatory organ
12 Role of lymhoid Markers in toxicological immunohistochemistry
13 Mucosa-associated lymphoid tissue
14 Markers of neuro Immunohistochemistry
15 Rat astrocytomas and malignant reticulosis
16 Bone Marrow Markers
17 Aquatic Immunohistochemistry Toxicology
18 Importance of Comparative Genomic Hybridization in rodent tumour
Autoren-Porträt
Syed A Aziz, Ph.D. Regulatory Toxicology Research Division, Bureau of Chemical Safety
Food Directorate, Health Products and Food Branch
Health Canada
Adjunct professor, Faculty of Medicine Dept. of Pathology
University of Ottawa
Rekha Mehta, Ph.D.
Regulatory Toxicology Research Division, Bureau of Chemical Safety
Food Directorate, Health Products and Food Branch
Health Canada.
Bibliographische Angaben
- 2015, 1st ed. 2016, XI, 231 Seiten, 3 farbige Abbildungen, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Syed A. Aziz, Rekha Mehta
- Verlag: Springer, Berlin
- ISBN-10: 1493915150
- ISBN-13: 9781493915156
- Erscheinungsdatum: 24.12.2015
Sprache:
Englisch
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