Textbook of Hemophilia
(Sprache: Englisch)
The Textbook of Hemophilia has become a definitive resource for all those managing hemophilia patients. It covers all the common and rare bleeding disorders, both in terms of clinical management as well as the genetic, laboratory, financial and...
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The Textbook of Hemophilia has become a definitive resource for all those managing hemophilia patients. It covers all the common and rare bleeding disorders, both in terms of clinical management as well as the genetic, laboratory, financial and psychological aspects.
This second edition covers all the latest developments in the field of hemophilia, with new chapters on:
* the genetic and molecular basis of inherited blood disorders
* how to manage adolescent and older patients
* emergency medicine and inherited blood disorders
* national hemophilia databases
Drawing on the vast experience of the authors, the aim of this textbook remains the same - to improve the care of patients suffering from hemophilia. The book is full of detailed guidance and advice on everyday clinical questions making it invaluable to all trainee and practicing hematologists.
Klappentext zu „Textbook of Hemophilia “
The Textbook of Hemophilia has become the definitive resource on all aspects of hemophilia, including diagnosis, management and treatment. It covers all the common and rare bleeding disorders, both in terms of clinical management as well as the genetic, laboratory, financial and psychological aspects. Complications of hemophilia care are well covered in chapters on inhibitors, musculoskeletal problems and transfusion-transmitted disease. This new edition includes all the latest developments in the field of hemophilia, including the molecular basis of the disease, the role of factors in coagulation, epidemiology, pharmacokinetics, treatment inhibitors and musculoskeletal aspects of the disease. It contains a new chapter on chronic pain management and coverage of new developments such as gene therapy, highlights controversial issues, and provides advice for everyday clinical questions.
The Textbook of Hemophilia has become the definitive resource on all aspects of hemophilia, including diagnosis, management and treatment. It covers all the common and rare bleeding disorders, both in terms of clinical management as well as the genetic, laboratory, financial and psychological aspects. Complications of hemophilia care are well covered in chapters on inhibitors, musculoskeletal problems and transfusion-transmitted disease. This new edition includes all the latest developments in the field of hemophilia, including the molecular basis of the disease, the role of factors in coagulation, epidemiology, pharmacokinetics, treatment inhibitors and musculoskeletal aspects of the disease. It contains a new chapter on chronic pain management and coverage of new developments such as gene therapy, highlights controversial issues, and provides advice for everyday clinical questions.
Inhaltsverzeichnis zu „Textbook of Hemophilia “
List of Contributors.Historical introduction (Christine A. Lee).
Part I: Introduction.
1 Overview of Hemostasis (Kathleen Brummel Ziedins and Kenneth G. Mann).
2 Cellular processing of Factor VIII and Factor IX (Michael U. Callaghan and Randal J. Kaufman).
Part II: Hemophilia A.
3 Molecular Basis of Hemophilia A (Geoffrey Kemball-Cook and Keith Gomez).
4 Phenotypic/genotypic relationship (Kathelijn Fischer and H. Marijke van den Berg).
5 Prophylaxis (Kathelijn Fischer and H. Marijke van den Berg).
6 Continuous Infusion of Coagulation Products in Hemophilia (Angelika Batorova and Uri Martinowitz).
Part III: Inhibitors to Factor VIII.
7 Inhibitors to Factor VIII - Immunology (Jean-Marie R. Saint-Remy and Marc G. Jacquemin).
8 Genetic and environmental risk factors for FVIII inhibitor development (Jan Astermark).
9 Inhibitors to Factor VIII - Mild and Moderate Hemophilia (Kathelijne Peerlinck and Marc Jacquemin).
10 Inhibitors to Factor VIII/IX: Immune Tolerance (Donna DiMichele).
11 Inhibitors to factor VIII: treatment of acute bleeds (Claude Negrier).
Part IV: Acquired Hemophilia.
12 Acquired Inhibitors to Factor VIII (Suman L. Sood and Craig M. Kessler).
Part V: Hemophilia B.
13 Hemophilia B - Molecular Basis (Keith Gomez).
14 Factor IX Inhibitors in Hemophilia B (Jeanne M. Lusher and Meera Chitlur).
15 Treatment of Inhibitors in Hemophilia B (Anand Tandra and Amy D. Shapiro).
Part VI: Pharmacokinetics of Factors VIII & IX.
16 Pharmacokinetics (Sven Björkman and Erik E. Berntorp).
Part VII: Hemophilia - birth to old age.
17 The Neonate with Hemophilia (Angela E. Thomas and Elizabeth Chalmers).
18 Work-up of a Bleeding Child (Manuel D. Carcao and Victor S. Blanchette).
19 Care of the Child with Hemophilia (Rolf Ljung).
20 Adolescence (Martti A Siimes).
21 Old age medicine and hemophilia (Evelien P. Mauser-Bunschoten and R.E.G. Schutgens).
Part VIII: Products used to Treat Hemophilia.
22 Products Used to Treat Hemophilia: Recombinant
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Products (Akira Yoshioka).
23 Products Used to Treat Hemophilia: Plasma-Derived Coagulation Factor Concentrates (Paul Giangrande).
24 Products Used to Treat Hemophilia: Recombinant Factor VIIa (Ulla Hedner).
25 Products Used to Treat Hemophilia: Dosing (Miguel A. Escobar).
26 Products Used to Treat Hemophilia: Regulation (Albert Farrugia).
Part IX: Musculoskeletal.
27 Joint Replacement (Nicholas Goddard).
28 Synovioarthesis in Hemophilia (E. Carlos Rodriguez-Merchan
23 Products Used to Treat Hemophilia: Plasma-Derived Coagulation Factor Concentrates (Paul Giangrande).
24 Products Used to Treat Hemophilia: Recombinant Factor VIIa (Ulla Hedner).
25 Products Used to Treat Hemophilia: Dosing (Miguel A. Escobar).
26 Products Used to Treat Hemophilia: Regulation (Albert Farrugia).
Part IX: Musculoskeletal.
27 Joint Replacement (Nicholas Goddard).
28 Synovioarthesis in Hemophilia (E. Carlos Rodriguez-Merchan
... weniger
Autoren-Porträt
Christine A. Lee MA, MD, DSc, FRCP, FRCPathEmeritus Professor of Haemophilia, University of London;Honorary Consultant Haematologist, Oxford Haemophilia & Thrombosis Centre, Oxford, UKErik E. Berntorp MD, PhDProfessor of Haemophilia, Lund University, Malmö Centre for Thrombosis and Haemostasis, Skåne University Hospital, Malmö, SwedenW. Keith Hoots MDDirector, Division of Blood Diseases and Resources, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD;Professor of Pediatrics and Internal Medicine, University of Texas Medical School at Houston,Houston, TX, USA
Bibliographische Angaben
- 2010, 2nd ed., XII, 464 Seiten, mit Abbildungen, Maße: 22,8 x 28,1 cm, Gebunden, Englisch
- Eds.: Lee, Christine A.; Berntorp, Erik E.; Hoots, W. Keith
- Herausgegeben: Christine A. Lee, Erik E. Berntorp, W. Keith Hoots
- Verlag: Wiley & Sons
- ISBN-10: 1405169141
- ISBN-13: 9781405169141
Sprache:
Englisch
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