The Role of Brain Dopamine
(Sprache: Englisch)
As in other volumes in the series, this newest volume conveys up-to-date knowledge in a clear and straightforward manner. It begins with a survey of the neurobiological functions of the brain, with the emphasis on Parkinson's disease. This is followed by a...
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Klappentext zu „The Role of Brain Dopamine “
As in other volumes in the series, this newest volume conveys up-to-date knowledge in a clear and straightforward manner. It begins with a survey of the neurobiological functions of the brain, with the emphasis on Parkinson's disease. This is followed by a presentation of the role of dopamine in the regulation of human anterior pituitary function. The final two chapters concentrate on the dopamine receptors: first, the binding sites are characterized and the biochemical and physiological consequences of dopamine-receptor stimulation are discussed and, finally, there is a report on the topology of a dopamine-receptor model that can account comprehensively for agonists and antagonists.
Inhaltsverzeichnis zu „The Role of Brain Dopamine “
- The Role of Dopamine in the Control of Neurobiological Functions- Parkinson's Disease
- Morphological Basis for the Pathobiochemistry of the Nigrostriatal Dopamine Systems
- Pathobiochemistry of Parkinson's Disease
- Protein Phosphorylation and Synthesis
- Molecular Plasticity of the Nigrostriatal DA System in Man
- Presynaptic Feedback Regulation
- Therapeutic Consequences of Autoreceptor Stimulation
- Basic Principles of Receptor Regulation
- Transneuronal Feedback Regulation
- Denervation Supersensitivity
- Neuronal Sprouting and Re-innervation by Grafts
- Neuronal Reserve Capacity
- DA as a Hormone
- Evidence for a Lack of Mitochondria Containing Monoamine Oxidase in the Nigrostriatal DA System
- Vulnerability of Dopaminergic Substantia Nigra Neurons
- DA in the Control of Endocrine Activity
- DA and Body Weight
- Catecholamines in the Spinal Cord
- Behaviour Related to Unbalanced Neural Loops Involving a Dopaminergic System
- Senile Dementia of the Alzheimer Type
- A DA Hypothesis of Schizophrenia
- DA in Affective Disorders
- References
- Clinical Aspects of Dopamine in the Regulation of Human Anterior Pituitary Function
- Regulation of Prolactin Secretion
- Clinical Features of Hyperprolactinaemia
- Diagnosis of Hyperprolactinaemia
- Natural History of Prolactinomas
- Therapy
- Macroprolactinomas
- Dopamine and LH Secretion
- Dopamine in Growth Hormone Secretion
- Dopamine Agonist Therapy for Acromegaly
- Dopamine and ACTH Secretion
- Conclusions
- References
- Dopamine Receptors in the Central Nervous System
- Receptors and Second Messengers
- Second Messengers and Dopamine Receptors
- Selective D1 Receptor Agonists and Antagonists
- Selective D2 Receptor Agonists and Antagonists
- Binding Sites for Dopamine Receptor Ligands
- In Vitro Binding Assays
- Autoradiography
- Biochemical and Physiological Manifestations of Dopamine Receptor Stimulation
- D1 Receptors
- D2 Receptors
- Behavioural Manifestations of
... mehr
Dopamine Receptor Stimulation
- Conclusions
- References
- Topology of Dopamine Receptors
- Dopamine Agonists
- Dopamine Antagonists
- Unsolved Problems: D1/D2 Specificity and Partial Agonists
- Conclusion
- References
- Conclusions
- References
- Topology of Dopamine Receptors
- Dopamine Agonists
- Dopamine Antagonists
- Unsolved Problems: D1/D2 Specificity and Partial Agonists
- Conclusion
- References
... weniger
Bibliographische Angaben
- 1989, IX, 55 Seiten, 29 farbige Abbildungen, Maße: 21 x 27,7 cm, Kartoniert (TB), Englisch
- Verlag: Springer, Berlin
- ISBN-10: 3540500405
- ISBN-13: 9783540500407
Sprache:
Englisch
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