The Role of Microtubules in Cell Biology, Neurobiology, and Oncology
(Sprache: Englisch)
This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and...
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This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and investigates the potential of microtubules in cancer therapy.
Klappentext zu „The Role of Microtubules in Cell Biology, Neurobiology, and Oncology “
This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and investigates the potential of microtubules in cancer therapy.
Inhaltsverzeichnis zu „The Role of Microtubules in Cell Biology, Neurobiology, and Oncology “
1. An Overview of Compounds that Interact with Tubulin and their Effects on Microtubule Assembly.Ernest Hamel2. Molecular Mechanisms of Micotubule Acting Cancer Drugs.J. J. Correia and S. Lobert3. Microtubule Dynamics: Mechanisms and Regulation by Microtubule-Associated Proteins and Drugs in vitro and in cellsMary Ann Jordan and Leslie Wilson4. Microtubule Associated Proteins (MAPs) and Microtubule Interacting Proteins: Regulators of Microtubule DynamicsMaria Kavallaris, Sima Don, Nicole M. Verrills5. The Post-Translational Modifications of TubulinRichard F. Ludueña, and Asok Banerjee6. The Isotypes of Tubulin: Distribution and Functional SignificanceRichard F. Ludueña, and Asok Banerjee7. The Tubulin SuperfamilyRichard F. Ludueña, and Asok Banerjee8. Tubulin Proteomics in CancerPascal Verdier Pinard, Fang Wang, Ruth Hogue Angeletti , Susan Band Horwitz, and George A. Orr9. Tubulin and Microtubule StructuresEva Nogales and Kenneth H. Downing10. Destabilizing Agents: Peptides and DepsipeptidesLee M. Greenberger and Frank Loganzo11. Molecular Features of the Interaction of Colchicine and Related Structures with TubulinSusan L. Bane12. Antimicrotubule Agents that Bind Covalently to TubulinDan L. Sackett13. Microtubule Stabilizing AgentsSusan Band Horwitz and Tito Fojo14. Mechanisms of Resistance to Drugs that Interfere with Microtubule AssemblyFernando Cabral15. Resistance to Microtubule Targeting Drugs: Part IIParaskevi Giannakakou and James P. Snyder16. Microtubule Stabilizing Agent in Clinical Oncology: The TaxanesChris H. Takimoto and Muralidhar Beeram17. Investigational anti-cancer agents targeting the microtubule.Lyudmila A. Vereshchagina, Orit Scharf, and A. Dimitrios Colevas18. MicrotubuleDamaging Agents and ApoptosisManon Carre and Diane Brauger19. Microtubule targeting agents and the tumor vasculatureRaffaella. Giavazzi, K. Bonezzi and Giulia Taraboletti20. Neurodegenerative Diseases: Tau Proteins in Neurodegenerative Diseases Other Than Alzheimer's
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DiseaseAndré Delacourte, Nicolas Sergeant and Luc Buée21. Structure, Function and Regulation of the Microtubule Associated Protein TauJanis Bunker and Stuart C. Feinstein
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Bibliographische Angaben
- 2008, 587 Seiten, Maße: 18,3 x 26 cm, Gebunden, Englisch
- Herausgegeben:Fojo, Antonio Tito
- Herausgegeben: Antonio Tito Fojo
- Verlag: Humana Press
- ISBN-10: 1588292940
- ISBN-13: 9781588292940
- Erscheinungsdatum: 11.06.2008
Sprache:
Englisch
Rezension zu „The Role of Microtubules in Cell Biology, Neurobiology, and Oncology “
From the reviews:"This book is appropriate for laboratories with an interest in the biology of microtubules ... . Each chapter is nicely illustrated, well referenced, and offers a timely evaluation of what is known about tubulin and microtubules, including how they are targeted therapeutically. ... The color insert and the accompanying CD-ROM with all color figures are helpful. This is an excellent all-around reference appropriate for researchers or clinicians interested in the basic science of tubulins, microtubules, related diseases, and targeted therapy."(John D. Robertson, Doody's Review Service, January, 2009)
"This book offers a wide and detailed discussion of drugs and methods for studying tubulins and microtubules ... . The book is easy-reading and well organized by ... well-detailed and itemized methodology of study, a helpful conclusion including tips for future interested investigators, and a long list of references serving a specific source of search. ... Chapters added in the end of the book ... very nicely wrap up the book for those interested in these areas and hopefully intending to acquire acknowledgement about it." (Fábio Luís Forti, Brazilian Journal of Pharmaceutical Sciences, Vol. 47 (2), Summer, 2011)
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