Toxicology and Human Environments

1. Human Environments: Definition, Scope and the Role of Toxicology


Ernest Hodgson


2. Estimating Human Exposure: Improving Accuracy with Chemical Markers


Roger C. Cochran and Jeffrey H. Driver


3. Metabolism of Xenobiotics Human Environments


Edward Croom


4. Toxic Endpoints in the Study of Human Exposure to Environmental Chemicals


Andrew D. Wallace


5. Pesticide Regulations: Exposure-Dose Modeling from FIFRA to FQPA


James B. Knaak, Cecilla Tan and Curt C. Dary


6. Occupational Chemicals: Metabolism, Toxicity and Mode of Action


Sheila Flack and Leena A. Nylander-French


7. Chemicals of Military Deployments: Revisiting Gulf War Syndrome in Light of New Information


A.A. Brimfield


8. Pharmaceuticals in the Environment: Lessons Learned for Reducing Uncertainties in Environmental Risk Assessment


Bryan W. Brooks, Jason P. Berninger, Lauren A. Kristofco, Alejandro J. Ramirez, Jacob K. Stanley and Theodore W. Valenti


9. Quantitative Risk Assessment Methods for Cancer and Non-Cancer Effects


Ronald E. Baynes


10. Human Health Risk Assessment for Contaminated Properties


Atul M. Salhotra


11. The Future of Human Health Risk Assessment of Environmental Chemicals.


Ernest Hodgson


12. Ecological Risk Assessment


Damian Shea and Waverly Thorsen


13. Metabolic Interactions of Environmental Toxicants in Humans


Ernest Hodgson


14. Toxins and Venoms


Ernest Hodgson


15. Summary and Conclusions

Ernest Hodgson

Hodgson, Ernest

Dr Ernest Hodgson, Distinguished Professor Emeritus, North Carolina State University and Executive Director, Foundation for Toxicology and Agromedicine was educated at King's College of the University of Durham (now the University of Newcastle), Oregon State University and the University of Wisconsin. At North Carolina State University since 1961 he was a William Neal Reynolds Professor and Head of the newly formed Department of Toxicology. He was also one of the founders of the three university (East Carolina University, North Carolina State University and North Carolina A&T University) program in agromedicine, an organization which led to the formation of the North Carolina Agromedicine Institute.

Dr. Hodgson has conducted research on xenobiotic biochemistry for several decades, has authored c. 400 peer-reviewed papers in this area, and is editor and part author of several monographs. Most recently his research has focused on human studies utilizing human hepatocytes and sub-cellular preparations. Currently involved as a collaborator with Dr Michael Roe in RNAseq studies of genome-wide effects of environmental chemicals. From 1961 until his retirement he was supported by extramural funding, primarily from NIH (NIEHS) and the US Army.

Dr Hodgson is also editor and contributing author of toxicology textbooks (Textbook of Modern Toxicology and Molecular and Biochemical Toxicology, both currently in their 4th editions) and is a lexicographer (Dictionary of Toxicology, under revision for a 3rd edition and a Dictionary of Agromedicine, being created for the NC Agromedicine Institute). He is well recognized for his role as a teacher of toxicology. In addition to his role as editor and part author of textbooks he has trained some 40 graduate students and 20 post-doctoral research associates.

His service on federal study sections and other federal panels has been extensive and includes the following agencies. NIH,

Praise for the series: "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal