Chemical Synthesis of Hormones, Pheromones and Other Bioregulators (PDF)

Many small molecules occur naturally as "messenger" chemicals which
regulate the behaviour and functions of microbes, plants, insects
and animals. Examples include hormones, pheromones, phytoalexins,
and antifeedants. These biofunctional molecules are of great
interest to researchers in helping develop our understanding of
biological function and in the development of new drugs. However
extracting them from nature can be prohibitively expensive, so
there is great interest in devising methods of synthesising them
from simple starting materials in the laboratory.

Chemical Synthesis of Hormones, Pheromones and Other
Bioregulators is an introduction to the techniques and
strategies for the synthesis of biofunctional small molecules.
Topics include:

* what are biofunctional molecules?

* why must biofunctional molecules be synthesized?

* how can we synthesize biofunctional molecules?

* the synthesis of phytohormones, phytoalexins and other
biofunctional molecules of plant origin

* the synthesis of insect juvenile hormones and antifeedants

* the synthesis of pheromones and the significance of chirality
in pheromone science

* the synthesis of microbial hormones and pheromones,
antibiotics, and other biofunctional molecules of microbial
origin

* the synthesis of marine antifeedants and medicinal
candidates

* a synthetic examination of incorrectly proposed structures of
biomolecules

* reflections on science as a human endeavor

Drawing on a career of almost 50 years researching and teaching
this subject, Kenji Mori's Chemical Synthesis of Hormones,
Pheromones and Other Bioregulators is a must-have textbook for
students and researchers of organic synthesis and natural products,
and a stimulating and inspiring account of a distinguished chemical
career.