Combinatorial Chemistry / Methods and Principles in Medicinal Chemistry Bd.26 (PDF)
From Theory to Application
(Sprache: Englisch)
This revolutionary method enables organic and medicinal chemists to synthesize thousands or even millions of potentially interesting compounds in a single reaction sequence. Combined with current methods of high throughput analysis, combinatorial methods...
sofort als Download lieferbar
Printausgabe 319.00 €
eBook (pdf) -10%
286.99 €
- Lastschrift, Kreditkarte, Paypal, Rechnung
- Kostenloser tolino webreader
Produktdetails
Produktinformationen zu „Combinatorial Chemistry / Methods and Principles in Medicinal Chemistry Bd.26 (PDF)“
This revolutionary method enables organic and medicinal chemists to synthesize thousands or even millions of potentially interesting compounds in a single reaction sequence. Combined with current methods of high throughput analysis, combinatorial methods have almost completely replaced the traditional step-by-step synthesis of potential drugs.
Retaining its practice-oriented approach, this new edition has been thoroughly updated to reflect recent developments in parallel synthesis, while a new chapter on screening complements the overview of combinatorial strategy and synthetic methods. The result is a handbook tailored to the needs of the industry, with almost all the authors affiliated with leading pharmaceutical companies.
From the contents:
Purification Principles in High-Speed Solution Phase Synthesis
Linkers for Solid-Phase Organic Synthesis (SPOS) and Combinatorial Approaches on Solid Support
Cyclative Cleavage - A Versatile Concept in Solid-Phase Organic Chemistry
C-C Bond Forming Reactions
Combinatorial Synthesis of Heterocycles
Polymer-Supported Reagents: Preparation and Use in Parallel Organic Synthesis
Encoding Strategies for Combinatorial Libraries
Automation and Devices for Combinatorial Chemistry and Parallel Organic Synthesis
Assays for High Throughput Screening in Drug Discovery
Computer-Assisted Library Design
Appendix: Cheminformatics and Web Resources for Combinatorial Chemistry
For organic and medicinal chemists, chemists in industry, and the pharmaceutical industry.
Retaining its practice-oriented approach, this new edition has been thoroughly updated to reflect recent developments in parallel synthesis, while a new chapter on screening complements the overview of combinatorial strategy and synthetic methods. The result is a handbook tailored to the needs of the industry, with almost all the authors affiliated with leading pharmaceutical companies.
From the contents:
Purification Principles in High-Speed Solution Phase Synthesis
Linkers for Solid-Phase Organic Synthesis (SPOS) and Combinatorial Approaches on Solid Support
Cyclative Cleavage - A Versatile Concept in Solid-Phase Organic Chemistry
C-C Bond Forming Reactions
Combinatorial Synthesis of Heterocycles
Polymer-Supported Reagents: Preparation and Use in Parallel Organic Synthesis
Encoding Strategies for Combinatorial Libraries
Automation and Devices for Combinatorial Chemistry and Parallel Organic Synthesis
Assays for High Throughput Screening in Drug Discovery
Computer-Assisted Library Design
Appendix: Cheminformatics and Web Resources for Combinatorial Chemistry
For organic and medicinal chemists, chemists in industry, and the pharmaceutical industry.
Inhaltsverzeichnis zu „Combinatorial Chemistry / Methods and Principles in Medicinal Chemistry Bd.26 (PDF)“
Purification Principles in High-Speed Solution Phase Synthesis (S. Weinbrenner, C. Tzschucke) Linkers for Solid-Phase Organic Synthesis (SPOS) and Combinatorial Approaches on Solid Support (W. Bannwarth) Cyclative Cleavage - A Versatile Concept in Solid-Phase Organic Chemistry (J. Pernerstorfer) C-C Bond Forming Reactions (W. Brill, G. Papeo) Combinatorial Synthesis of Heterocycles (E. Felder, A. Marzinzik) Polymer-Supported Reagents: Preparation and Use in Parallel Organic Synthesis (B. Hinzen, M. Hahn) Encoding Strategies for Combinatorial Libraries (B. Hinzen) Automation and Devices for Combinatorial Chemistry and Parallel Organic Synthesis (C. Zechel) Computer-Assisted Library Design (A. Dominik) Assays for High Throughput Screening in Drug Discovery (C. Apfel, T. Enderle) Appendix: Cheminformatics and Web Resources for Combinatorial Chemistry
Autoren-Porträt
Willi Bannwarth is full Professor for Organic Chemistry at the Albert-Ludwigs University Freiburg (Germany). Having studied Chemistry in Münster and Konstanz, he worked as a postdoctoral fellow with Sir A. Battersby in Cambridge (UK). In 1979, he joined Roche in Basel (Switzerland) where he was head of nucleotide and peptide chemistry and later was named head of combinatorial chemistry, a technique which he had introduced at Roche. In 1996 he moved to Byk Gulden Pharmaceuticals (now Altanapharma) in Konstanz to build a cominatorial chemistry facility there. In 1999 he was appointed professor for Organic chemistry at the University of Freiburg where he focuses on combinatorial and bioorganic chemistry.
Bibliographische Angaben
- 2006, 2. überarbeitete und ergänzte Auflage, 672 Seiten, Englisch
- Herausgegeben: Willi Bannwarth, Berthold Hinzen
- Verlag: Wiley-VCH GmbH
- ISBN-10: 3527607382
- ISBN-13: 9783527607389
- Erscheinungsdatum: 12.05.2006
Abhängig von Bildschirmgröße und eingestellter Schriftgröße kann die Seitenzahl auf Ihrem Lesegerät variieren.
eBook Informationen
- Dateiformat: PDF
- Größe: 20 MB
- Mit Kopierschutz
Sprache:
Englisch
Kopierschutz
Dieses eBook können Sie uneingeschränkt auf allen Geräten der tolino Familie lesen. Zum Lesen auf sonstigen eReadern und am PC benötigen Sie eine Adobe ID.
Kommentar zu "Combinatorial Chemistry / Methods and Principles in Medicinal Chemistry Bd.26"
0 Gebrauchte Artikel zu „Combinatorial Chemistry / Methods and Principles in Medicinal Chemistry Bd.26“
Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
---|
Schreiben Sie einen Kommentar zu "Combinatorial Chemistry / Methods and Principles in Medicinal Chemistry Bd.26".
Kommentar verfassen