DNA Methyltransferases - Role and Function / Advances in Experimental Medicine and Biology Bd.1389 (PDF)
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This 2nd edition of the book on DNA methyltransferases has been comprehensively updated to reflect many novel research findings regarding the structure, function, and technology of these enzymes that have emerged over the past 6 years.
As the previous edition, this 2nd edition explains the biochemical properties of DNA methyltransferases, describing their structures, mechanisms and biological roles in bacteria, humans and plants. It also discusses the biological processes of reading DNA methylation and the mechanisms of DNA demethylation. This volume highlights the newest findings on DNA methyltransferase inhibitors and their use in cancer therapy as well as the latest epigenome editing systems based on these enzymes.
Overall, this 2nd edition comprehensively summarizes the current state of research in the field of DNA methylation and DNA methyltransferase and is essential reading for early career and advanced researchers in this exciting field.
Dr Renata Jurkowska is a molecular biologist with general interests in epigenetics, stem cells and lung biology. She obtained her M.Sc. degree in Biotechnology at Warsaw University (Poland) and went on to complete her PhD in Biochemistry and two postdocs in Germany, where she investigated the specificity and molecular mechanism of mammalian DNA methyltransferases and other epigenetic enzymes for 10 years. In 2015, she joined BioMed X Innovation Center (Germany) as a Principal Investigator, where she worked at the interface between academia and industry, leading a biomedical preclinical project in the field of respiratory medicine and epigenetics. In September 2019 she was appointed Senior Lecturer in the School of Biosciences at Cardiff University, UK. Her current research focuses on understanding how epigenetic regulation drives cellular identity in the healthy
- 2022, 2nd ed. 2022, 562 Seiten, Englisch
- Herausgegeben: Albert Jeltsch, Renata Z. Jurkowska
- Verlag: Springer Nature Switzerland
- ISBN-10: 303111454X
- ISBN-13: 9783031114540
- Erscheinungsdatum: 09.11.2022
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- Größe: 22 MB
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