Management of Chemical and Biological Samples for Screening Applications (PDF)
(Sprache: Englisch)
Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large
screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this...
screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this...
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Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large
screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline, from compound
acquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program.
screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline, from compound
acquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program.
Inhaltsverzeichnis zu „Management of Chemical and Biological Samples for Screening Applications (PDF)“
AN INTRODUCTION TO SAMPLE MANAGEMENT What is Sample Management? QUALITY IN COMPOUND MANAGEMENT Generating a High Quality Compound Collection Assessing Compound Quality Maintaining and Delivering Quality with Compound Management Obtaining and Maintaining High Quality Tissue Samples: Scientific and Technical Considerations for Evidence Based Practice EFFICIENT SAMPLE MANAGEMENT PROCESS The Lean Sample Management Laboratory SAMPLE/COMPOUND LOGISTICS Sample Distribution AUTOMATION IN COMPOUND MANAGEMENT Development of Automation in Sample Management Acoustic Technology Large Scale Automated Storage and Retrieval of Biological Samples at -80°C INFORMATION TECHNOLOGY Information Technology Systems for Sample Management BIOBANKING Managing the American Tissue Culture Collection: The Global Bioresource Center Establishing a Tissue Biobank FUTURE PERSPECITVES What does an HTS File of the Future Look Like? The Impact of Future Technologies within Biobanking Outsourcing Sample Management
Autoren-Porträt
Mark Wigglesworth manages the UK Lead Optimization area of Sample Management Technologies for GlaxoSmith-Kline. Over the past 10 years Mark has managed large and small compound stores, assay ready plate production and compound set provision, as well as interacting with many areas of drug discovery. Additionally, he has led several drug discovery programs and overseen multiple screening platforms providing structure activity relationship data within GlaxoSmithKline?s screening organizations.Now a freelance business consultant, Terry Wood retired in 2011 as the manager of the Liquid Store Centre of Emphasis at Pfizer?s world-wide R&D department, based in Sandwich (UK). He has been involved in the high-throughput screening process for the whole of his 25 year career with Pfizer. This has given him a first hand and broad knowledge about the challenges and caveats of assay design, development and
prosecution. His prime responsibility focused on the management of Pfizer?s extensive compound file, using a range of automated systems for sample preparation, storage and delivery.
Bibliographische Angaben
- 2012, 1. Auflage, 406 Seiten, Englisch
- Herausgegeben: Mark Wigglesworth, Terry Wood
- Verlag: Wiley-VCH
- ISBN-10: 3527645276
- ISBN-13: 9783527645275
- Erscheinungsdatum: 13.01.2012
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- Größe: 4.47 MB
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Englisch
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