Non-coding RNAs at the Cross-Road of Cardiometabolic Diseases and Cancer (PDF)

About the Author:

Prof. Paul Holvoet, an emeritus professor in Biomedicine at KU Leuven, Belgium, who co-authored more than 250 papers receiving more than 11,000 citations. He established the relation between oxidative stress and obesity, insulin resistance and metabolic syndrome, and the relationship between metabolic syndrome and acute cardiovascular disease. He contributed to the elucidation of the role of non-coding RNAs in the regulation of immune response, oxidative stress, insulin signaling, and inflammation in the pathogenesis of obesity, type 2 diabetes, non-alcoholic fatty liver disease, atherosclerosis, and cardiovascular diseases. He now uses his mechanistic knowledge in all these fields to compare non-coding RNAs' role in cancer progression.

He obtained European and US patents on markers of oxidative stress, which predict cardiometabolic diseases (2007). He recently received a European and US license about markers for identifying a patient at risk for experiencing one or more cardiovascular events and revising treatment (2018-2020). He obtained the honorary titles of Fellow of the American Heart Association and the European Society of Cardiology. He was a panel member of the European Research Council (2007-2013) and reviewed papers and research proposals submitted to high-impact journals and funding organizations in Europe and NIH-US. He was an associate editor of the journal Arteriosclerosis, Thrombosis and Vascular Biology for over twenty years, and first an associated editor, and between 2013 and 2017, a deputy editor of Cardiovascular Research.

Together with Tine Holvoet, sociologist, he is a co-founder of Teamtank, promoting interdisciplinary collaboration. As an example of this, Paul Holvoet collaborated with the illustrator Pieterjan Ginckels in editing this book.

About the Illustrator:

Pieterjan Ginckels is an artist and architect. "Our lives are hyper-real, and we feel the urge to continuously pimp,