Pharmaceutical Process Chemistry for Synthesis (ePub)
Rethinking the Routes to Scale-Up
(Sprache: Englisch)
There is a need to explain that generic versions of a drug may
not be manufactured by the same process as brand-name drugs and
that the different processes may have dramatically different
environmental impacts. Two global forces are at odds
today--the...
not be manufactured by the same process as brand-name drugs and
that the different processes may have dramatically different
environmental impacts. Two global forces are at odds
today--the...
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There is a need to explain that generic versions of a drug may
not be manufactured by the same process as brand-name drugs and
that the different processes may have dramatically different
environmental impacts. Two global forces are at odds
today--the push for "greener" processes and the push for lower
drug prices. This book brings this conflict into sharp focus by
discussing in detail the published process chemistry for
top-selling small molecule drugs.
Providing insights about process route selection, choice of
reagents, and reaction conditions, Pharmaceutical Process
Chemistry for Synthesis guides process chemists in identifying
best processes for manufacturing these blockbuster drugs as they
lose patent protection. Further, it highlights the strategies and
methodology that might be useful for expediting the process
research and development of the blockbusters of the future.
Written from a refreshingly objective perspective, this book is
essential for process chemists who need to devise practical
syntheses for increasingly complex drugs in a constantly decreasing
time frame.
not be manufactured by the same process as brand-name drugs and
that the different processes may have dramatically different
environmental impacts. Two global forces are at odds
today--the push for "greener" processes and the push for lower
drug prices. This book brings this conflict into sharp focus by
discussing in detail the published process chemistry for
top-selling small molecule drugs.
Providing insights about process route selection, choice of
reagents, and reaction conditions, Pharmaceutical Process
Chemistry for Synthesis guides process chemists in identifying
best processes for manufacturing these blockbuster drugs as they
lose patent protection. Further, it highlights the strategies and
methodology that might be useful for expediting the process
research and development of the blockbusters of the future.
Written from a refreshingly objective perspective, this book is
essential for process chemists who need to devise practical
syntheses for increasingly complex drugs in a constantly decreasing
time frame.
Inhaltsverzeichnis zu „Pharmaceutical Process Chemistry for Synthesis (ePub)“
1 Introduction. 2 Actos® (Pioglitazone Hydrochloride). 3 Lexapro® (Escitalopram Oxalate). 4 Efferox XR® (Venlafaxine Hydrochloride). 5 Seroquel® (Quetiapine Hemifumarate). 6 Singulair® (Montelukast Sodium). 7 Prevacid® (Lansoprazole). 8 Advair Diskus® (Salmeterol Xinafoate). 9 Lipitor® (Aatorvastatin Calcium). Index.
Autoren-Porträt von Peter J. Harrington
Peter J. Harrington is the founder of Better Pharma Processes, LLC, a consulting firm specializing in pharmaceutical process design and development. From 1988-2008, he worked for the Syntex Technology Center, later Roche Colorado, as a research fellow. Dr. Harrington has more than fifty patents and research publications, including reviews and abstracts, as well as the book Transition Metals in Total Synthesis (Wiley).
Bibliographische Angaben
- Autor: Peter J. Harrington
- 2011, 1. Auflage, 376 Seiten, Englisch
- Verlag: John Wiley & Sons
- ISBN-10: 0470922869
- ISBN-13: 9780470922866
- Erscheinungsdatum: 24.02.2011
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eBook Informationen
- Dateiformat: ePub
- Größe: 4.45 MB
- Mit Kopierschutz
Sprache:
Englisch
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