Pharmacogenomics of Human Drug Transporters (ePub)
Clinical Impacts
(Sprache: Englisch)
Sets the foundation for safer, more effective drug
therapies
With this book as their guide, readers will discover how to
apply our current understanding of the pharmacogenomics of drug
transporters to advance their own drug discovery and...
therapies
With this book as their guide, readers will discover how to
apply our current understanding of the pharmacogenomics of drug
transporters to advance their own drug discovery and...
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Produktinformationen zu „Pharmacogenomics of Human Drug Transporters (ePub)“
Sets the foundation for safer, more effective drug
therapies
With this book as their guide, readers will discover how to
apply our current understanding of the pharmacogenomics of drug
transporters to advance their own drug discovery and development
efforts. In particular, the book explains how new findings in the
field now enable researchers to more accurately predict drug
interactions and adverse drug reactions. Moreover, it sets the
foundation for the development of drug therapies that are tailored
to an individual patient's genetics.
Pharmacogenomics of Human Drug Transporters serves as a
comprehensive guide to how transporters regulate the absorption,
distribution, and elimination of drugs in the body as well as how
an individual's genome affects those processes. The book's eighteen
chapters have been authored by a team of leading pioneers in the
field. Based on their own laboratory and clinical experience as
well as a thorough review of the literature, these authors explore
all facets of drug transporter pharmacogenomics, including:
* Individual drug transporters and transporter families and their
clinical significance
* Principles of altered drug transport in drug-drug
interactions, pharmacotherapy, and personalized medicine
* Emerging new technologies for rapid detection of genetic
polymorphisms
* Clinical aspects of genetic polymorphisms in major drug
transporter genes
* Future research directions of drug transporter pharmacogenomics
and the prospect of individualized medicine
Pharmacogenomics of Human Drug Transporters opens the
door to new drug discovery and development breakthroughs leading to
safer and more effective customized drug therapies.The book is
recommended for pharmaceutical scientists, biochemists,
pharmacologists, clinicians, and genetics and genomics
researchers.
therapies
With this book as their guide, readers will discover how to
apply our current understanding of the pharmacogenomics of drug
transporters to advance their own drug discovery and development
efforts. In particular, the book explains how new findings in the
field now enable researchers to more accurately predict drug
interactions and adverse drug reactions. Moreover, it sets the
foundation for the development of drug therapies that are tailored
to an individual patient's genetics.
Pharmacogenomics of Human Drug Transporters serves as a
comprehensive guide to how transporters regulate the absorption,
distribution, and elimination of drugs in the body as well as how
an individual's genome affects those processes. The book's eighteen
chapters have been authored by a team of leading pioneers in the
field. Based on their own laboratory and clinical experience as
well as a thorough review of the literature, these authors explore
all facets of drug transporter pharmacogenomics, including:
* Individual drug transporters and transporter families and their
clinical significance
* Principles of altered drug transport in drug-drug
interactions, pharmacotherapy, and personalized medicine
* Emerging new technologies for rapid detection of genetic
polymorphisms
* Clinical aspects of genetic polymorphisms in major drug
transporter genes
* Future research directions of drug transporter pharmacogenomics
and the prospect of individualized medicine
Pharmacogenomics of Human Drug Transporters opens the
door to new drug discovery and development breakthroughs leading to
safer and more effective customized drug therapies.The book is
recommended for pharmaceutical scientists, biochemists,
pharmacologists, clinicians, and genetics and genomics
researchers.
Autoren-Porträt von Toshihisa Ishikawa, Richard B. Kim, Jörg König
TOSHIHISA ISHIKAWA, PhD, is Senior Scientist at RIKENYokohama Institute and Professor of Biochemistry, Molecular
Biology, and Pharmacogenomics at Yokohama City University's
Graduate School of Medicine. Previously, Dr. Ishikawa was the
Director of the Department of Research Technology Development at
Pfizer, Japan. A recipient of the Achievement Award from the
International Life Sciences Institute (ILSI), Dr. Ishikawa is also
the cofounder of the International Transporter Consortium
(ITC).
RICHARD B. KIM, MD, FRCPC, is Professor and Chair of the
Division of Clinical Pharmacology and Associate Chair for Research
in the Department of Medicine at the University of Western Ontario.
He is a Fellow of the American Association of Pharmaceutical
Scientists and an elected member of the American Society for
Clinical Investigation.
JÖRG KÖNIG, PhD, is Professor and Head
of the Molecular Biology Laboratories in the Department of Clinical
Pharmacology at the Friedrich-Alexander Universität
Erlangen-Nürnberg.
Bibliographische Angaben
- Autoren: Toshihisa Ishikawa , Richard B. Kim , Jörg König
- 2013, 1. Auflage, 440 Seiten, Englisch
- Verlag: John Wiley & Sons
- ISBN-10: 1118353250
- ISBN-13: 9781118353257
- Erscheinungsdatum: 11.03.2013
Abhängig von Bildschirmgröße und eingestellter Schriftgröße kann die Seitenzahl auf Ihrem Lesegerät variieren.
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- Dateiformat: ePub
- Größe: 5.90 MB
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Sprache:
Englisch
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