Vaccine Development and Manufacturing / Wiley Series on Biotechnology (PDF)

Vaccine Manufacturing and Production is an invaluable
reference on how to produce a vaccine - from beginning to end -
addressing all classes of vaccines from a
processing, production, and regulatory viewpoint. It will
provide comprehensive information on the various fields involved in
the production of vaccines, from fermentation, purification,
formulation, to regulatory filing and facility designs. In recent
years, there have been tremendous advances in all aspects of
vaccine manufacturing. Improved technology and growth media have
been developed for the production of cell culture with high cell
density or fermentation. Vaccine Manufacturing and
Production will serve as a reference on all aspects of vaccine
production by providing an in-depth description of the available
technologies for making different types of vaccines and the current
thinking in facility designs and supply issues. This book will
provide insight to the issues scientists face when producing a
vaccine, the steps that are involved, and will serve as
a reference tool regarding state-of-the-art vaccine
manufacturing technologies and facility set-up.

Highlights include:

* Comprehensive coverage of vaccine production : from a process
point of view- fermentation to purification to formulation
developments; from a production point of view - from facility
design to manufacturing; and from a regulatory point of view -
requirements from government agencies

* Authors from different major pharmaceutical and biotechnology
companies

* Describes the challenges and issues involved in vaccine
production and manufacturing of the different classes of vaccines,
an area not covered by other books currently on the market