Chemical Synthesis of Hormones, Pheromones and Other Bioregulators
(Sprache: Englisch)
Many small molecules occur naturally as "messenger" chemicals which regulate the behaviour and functions of microbes, plants, insects and animals. Examples include hormones, pheromones, phytoalexins, and antifeedants. These biofunctional molecules are of...
Leider schon ausverkauft
versandkostenfrei
Buch (Gebunden)
73.80 €
Produktdetails
Produktinformationen zu „Chemical Synthesis of Hormones, Pheromones and Other Bioregulators “
Klappentext zu „Chemical Synthesis of Hormones, Pheromones and Other Bioregulators “
Many small molecules occur naturally as "messenger" chemicals which regulate the behaviour and functions of microbes, plants, insects and animals. Examples include hormones, pheromones, phytoalexins, and antifeedants. These biofunctional molecules are of great interest to researchers in helping develop our understanding of biological function and in the development of new drugs. However extracting them from nature can be prohibitively expensive, so there is great interest in devising methods of synthesising them from simple starting materials in the laboratory.Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is an introduction to the techniques and strategies for the synthesis of biofunctional small molecules. Topics include:
* what are biofunctional molecules?
* why must biofunctional molecules be synthesized?
* how can we synthesize biofunctional molecules?
* the synthesis of phytohormones, phytoalexins and other biofunctional molecules of plant origin
* the synthesis of insect juvenile hormones and antifeedants
* the synthesis of pheromones and the significance of chirality in pheromone science
* the synthesis of microbial hormones and pheromones, antibiotics, and other biofunctional molecules of microbial origin
* the synthesis of marine antifeedants and medicinal candidates
* a synthetic examination of incorrectly proposed structures of biomolecules
* reflections on science as a human endeavor
Drawing on a career of almost 50 years researching and teaching this subject, Kenji Mori's Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is a must-have textbook for students and researchers of organic synthesis and natural products, and a stimulating and inspiring account of a distinguished chemical career.
Inhaltsverzeichnis zu „Chemical Synthesis of Hormones, Pheromones and Other Bioregulators “
PrefaceAbbreviations
1. Introduction - Biofunctional Molecules and Organic Synthesis
1.1 What are biofunctional molecules?
1.2 Developmental stages of studies on biofunctional molecules
1.3 Small amounts of the samples are now sufficient for the elucidation of the structures of biofunctional molecules
1.4 Why must biofunctional molecules be synthesized?
1.5 How can we synthesize biofunctional molecules?
1.6 What kinds of knowledge and techniques are necessary to synthesize biofunctional molecules?
References
2. Synthesis of Phytohormones, Phytoalexins and Other Biofunctional Molecules of Plant Origin
2.1 Phytohormones
2.2 Phytoalexins
2.3 Plant allelochemicals
2.4 Other bioactive compounds of plant origin
References
3. Synthesis of Insect Bioregulators other than Pheromones
3.1 Insect juvenile hormones
3.2 Insect antifeedants
3.3 Insect repellents
References
4. Synthesis of Pheromones
4.1 What are pheromones?
4.2 Methods for enantioselective synthesis
4.3 Why is it meaningful to synthesize enantiopure pheromones ?
4.4 Chiral pheromones whose single enantiomers show bioactivity
4.5 Chiral pheromones whose stereochemistry-bioactivity relationships are diverse and complicated
4.6 Significance of chirality in pheromone science
References
5. Synthesis of Biofunctional Molecules of Microbial Origin
5.1 Microbial hormones
5.2 Antibiotics
5.3 Other biofunctional molecules of microorganisms
References
6. Synthesis of Marine Bioregulators, Medicinals and Related Compounds
6.1 Marine natural products of ecological importance such as antifeedants
6.2 Marine natural products of medicinal interest
6.3 Glycosphingolipids and sphingolipids of
... mehr
medical interests
References
7. Synthetic Examination of Incorrectly Proposed Structures of Biomolecules
7.1 Origin of incorrect or obscure structures
7.2 Structure fabrications of historical interest
7.3 Incorrect structures resulting from inappropriate use of purification or analytical methods
7.4 Inappropriate structural proposal caused by problems in bioassay methods
7.5 Human errors are inevitable in chemistry, too
References
8. Conclusion -- Science as a Human Endeavor
8.1 Small molecules are also beautiful
8.2 Continuous efforts may bring something meaningful
8.3 Can a scientist eventually have a hope in future?
Acknowledgments
Index
References
7. Synthetic Examination of Incorrectly Proposed Structures of Biomolecules
7.1 Origin of incorrect or obscure structures
7.2 Structure fabrications of historical interest
7.3 Incorrect structures resulting from inappropriate use of purification or analytical methods
7.4 Inappropriate structural proposal caused by problems in bioassay methods
7.5 Human errors are inevitable in chemistry, too
References
8. Conclusion -- Science as a Human Endeavor
8.1 Small molecules are also beautiful
8.2 Continuous efforts may bring something meaningful
8.3 Can a scientist eventually have a hope in future?
Acknowledgments
Index
... weniger
Autoren-Porträt von Kenji Mori
Professor Kenji Mori has nearly 50 years experience researching and teaching the synthesis of biofunctional small molecules. He has been awarded the Japan Academy Prize (1981), the Silver Medal of the International Society of Chemical Ecology (1996), the American Chemical Society s Ernest Guenther Award in the Chemistry of Natural Products (1999), the Special Prize of the Society of Synthetic Organic Chemistry, Japan (2003), and the Frantisek Sorm Memorial Medal of the Academy of Sciences of the Czech Republic (2003). He is the author of "The Total Synthesis of Natural Products, Vol. 9" (Wiley, 1992), considered by many to be the authoritative volume on pheromone synthesis, and over 750 peer-reviewed research papers.
Bibliographische Angaben
- Autor: Kenji Mori
- 2010, 1. Auflage, 296 Seiten, Maße: 19,5 x 25,4 cm, Gebunden, Englisch
- Verlag: Wiley & Sons
- ISBN-10: 0470697245
- ISBN-13: 9780470697245
- Erscheinungsdatum: 29.09.2010
Sprache:
Englisch
Pressezitat
"This volume will reward the attention of anyone interested in organic synthesis, in natural products chemistry, or in chemical ecology. It should inspire more synthetic organic chemists to pay attention to current research on the roles played by small molecules in the lives of organisms, and it should encourage biologists and structural chemists to identify, contact, and collaborate with chemical colleagues who are mentally and physically equipped to carry out stereospecific syntheses of nature s signal molecules." (Journal of the American Chemical Society, 23 February 2011)Kommentar zu "Chemical Synthesis of Hormones, Pheromones and Other Bioregulators"
0 Gebrauchte Artikel zu „Chemical Synthesis of Hormones, Pheromones and Other Bioregulators“
Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
---|
Schreiben Sie einen Kommentar zu "Chemical Synthesis of Hormones, Pheromones and Other Bioregulators".
Kommentar verfassen