Fish Analysis for Drug and Chemicals Mediated Cellular Toxicity

Introduction to FISH analysis and Cellular Toxicity.- Discussion on anticancer drugs and its effect on reproductive and mental health.- Structural examinations of toxic agents and the effects of dose and metabolism.- Histological  changes and its correlation to exposure to toxic agents.- Statistical based approaches to risk assessment in Drug Toxicity.- Safety Evaluations.- Interpretation and application of toxicological data.

Prof. Ajit K. Saxena has received his Ph.D. in Genetics from Institute of Medical Sciences, B.H.U. in the year of 1990. During his Ph.D. he studied how anticancer drugs cause interference with normal development of the foetus and with special reference to the cause of abnormality during differentiation of male gonads which lead infertility including congenital anomalies. After receiving his Ph.D. degree he joined NIH funded Indo US project at AIIMS New Delhi; where he identified the role of novel antigen IL6 as a signal traducing agent in human glioblastoma. He also worked in various renowned Institutions of India and abroad including C.C.M.B., C.D.R.I., A.M.C., B.P.K.I.H.S. (Dharan) and B.H.U. Currently, he is working as a Professor of Clinical Genetics & Head in the Department of Pathology & Laboratory Medicine in All India Institute of Medical Sciences, Patna. He has successfully completed his administrative responsibilities as Head of the Department in prestigious institutions of India & abroad. In addition he has also served his duties as a Scientific Advisor to the Government. His research interest includes study of Gene Polymorphism in Congenital Neural Tube Defects/ Tumor Biology/Infertility and Cytokines gene expression in chronic wounds and hypertrophic scars. Currently, his research interest includes role of stem cells in translational research. Of note, he has published more than 100 articles in journals of international reputes with high citations. Based on his research and fellowship training, he has received several awards and honours, such as Gold Medal Award, Confer 'Vivek Ratan Award' and Millennium Award. Besides his research, teaching and administration he has also guided more than 36 students. He is serving as an editorial member of reputed journals like Biomedical Research, International Journal of Infertility. He has also served as a reviewer for several government funded project. He also acquired and completed several