Nonlinear Physics of DNA
(Sprache: Englisch)
Nichtlineare Effekte sind für das Verhalten von DNA-Molekülen von entscheidender Bedeutung und erst ihre Berücksichtigung ermöglicht eine sinnvolle Auswertung von experimentellen Daten.
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Nichtlineare Effekte sind für das Verhalten von DNA-Molekülen von entscheidender Bedeutung und erst ihre Berücksichtigung ermöglicht eine sinnvolle Auswertung von experimentellen Daten.
Klappentext zu „Nonlinear Physics of DNA “
The first edition of this book was the first on the physics of DNA to go beyond the simple (simplified) 'linear' approach, and it has since been found that the inclusion of nonlinear effects leads to a significantly improved interpretation of experimental data. This new edition naturally retains this approach, but has been completely revised, updated and expanded to cover recent developments.Beginning with introductory chapters on DNA structure and dynamics, the book also includes a comparison between linear and nonlinear approaches to the DNA molecule, a chapter devoted to the statistics of nonlinear excitations of DNA, and examples for the interpretation of experimental data on the dynamics of DNA in terms of nonlinear theory.Essential reading for researchers in biophysics and nonlinear physics, allowing biologists, chemists and physicists to continue developing new and improved techniques of investigating the DNA molecule.
Inhaltsverzeichnis zu „Nonlinear Physics of DNA “
CHAPTER 1 DNA STRUCTURE1.1 Chemical composition and primary structure1.2 Spatial geometry and secondary structure1.3 Forces stabilizing secondary structure1.4 Polymorphism1.5 Tertiary structure1.6 Approximate models of DNA structure1.7 Experimental methods of studying DNA structureCHAPTER 2 DNA DYNAMICS2.1 General picture of the internal mobility2.2 Twisting and bending motions2.3 Dynamics of bases2.4 Dynamics of sugar-phosphate backbone2.5 Conformational transitions2.6 Motions associated with local strand separation2.7 Approximate models of DNA dynamics2.8 Experimental methods of studying DNA dynamicsCHAPTER 3 DNA FUNCTIONING3.1 Physical aspects of DNA functioning3.2 Intercalation3.3 DNA-protein recognition3.4 Gene expression3.5 Regulation of gene expression3.6 ReplicationCHAPTER 4 LINEAR THEORY OF DNA4.1 The main mathematical models4.2 Statistics of linear excitations4.3 Scattering problem4.4 Linear theory and experimentCHAPTER 5 NONLINEAR THEORY OF DNA: IDEAL DYNAMICAL MODELS5.1 Nonlinear mathematical modeling: general principles and restrictions5.2 Nonlinear rod-like models5.3 Nonlinear double rod-like models5.4 Nonlinear models of higher levelsCHAPTER 6 NONLINEAR THEORY OF DNA: NON-IDEAL MODELS6.1 Effects of environment6.2 Effects of inhomogeneity
Autoren-Porträt von Ludmila Yakushevich
Ludmila V. Yakushevich is a Doctor of Science and leading research worker of the Laboratory of Physical and Chemical Mechanisms of Gene Expression, which is part of the Institute of Cell Biophysics of the Russian Academy of Sciences. The main research field is the dynamics of biopolymers, especially the nonlinear dynamics of DNA. The principal methods of investigations include theoretical physics and mathematical modeling.
Bibliographische Angaben
- Autor: Ludmila Yakushevich
- 2004, 2. Aufl., XV, 190 Seiten, 66 Schwarz-Weiß-Abbildungen, 65 Abbildungen, Maße: 17,5 x 24,5 cm, Gebunden, Englisch
- Verlag: Wiley-VCH
- ISBN-10: 3527404171
- ISBN-13: 9783527404179
- Erscheinungsdatum: 11.05.2004
Sprache:
Englisch
Rezension zu „Nonlinear Physics of DNA “
BioTec, Heft 11-12, November/Dezember 2004
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